Insulin And Metformin Together?

[Penguin]

Alright lads.

Is there any merit to using the two together? What I have always done is use slin and then when off used metformin inbetween.

Obviously I know metformin increases insulin sensitivity hence the question. Anyone here with any experience with this and what they thought to it? Or would you keep them both separate?

 

[BigChap92]

Alright lads.

Is there any merit to using the two together? What I have always done is use slin and then when off used metformin inbetween.

Obviously I know metformin increases insulin sensitivity hence the question. Anyone here with any experience with this and what they thought to it? Or would you keep them both separate?

Depends how experienced you are with insulin really and how well you can predict your response to a given dose, that requires a fair attention to detail on diet and a bit of monitoring. Otherwise it’s prob a bit on the risky side.

Not necessarily death or coma but hypos are unpleasant and Hypo’s are probably the most catabolic state you could ever ask to be in, the body will shit bricks and will strip proteins from everywhere so imagine what a hypo does to your newly acquired muscle gains. Hypos are gonna set you back aren’t they so is the increased sensitivity beneficial in that case? No it’s definitely not

Depends on how you’ve got it all lined up though mate.

To address the question though most ‘thinking men’ would probably opt cycle the two rather than run them in combination.

You’d run insulin for x amount of weeks which would eventually cause insulin resistance (you’d work that out from your daily blood glucose readings if you were performing them) and then you’d drop the insulin and you’d move onto to metformin and possibly some minor carb restriction on their off time to attempt to restore some insulin sensitivity.

I wouldn’t see the attraction to using both but you might.

In my view you don’t need metformin to make you more sensitive to exogenous slin, given the doses of exogenous slin used by most people. If you need to be more sensitive to 10-20iu of humalog there’s something up. Even 5iu... It’s just unnecessary isn’t it

The metformin and amelioration of fat loss part doesn’t really apply with exogenous slin, or to a bodybuilder. Unless you’re just piling food in with no care for calories in which case you’re fucked anyway ha!

So yeah, if I was gonna do I’d cycle the two but it’s entirely dependent on your logic as with all drugs use isn’t it mate? As with anything we use.

 

[Getbig25]

Can be used on off days from slin.

Depends on your insulin set up etc

 

[Max]

Simple answer - no.

Ins - 4-6 weeks - 2 weeks on metformin then back on slin.

 

[Penguin]

Depends how experienced you are with insulin really and how well you can predict your response to a given dose, that requires a fair attention to detail on diet and a bit of monitoring. Otherwise it’s prob a bit on the risky side.

Not necessarily death or coma but hypos are unpleasant and Hypo’s are probably the most catabolic state you could ever ask to be in, the body will shit bricks and will strip proteins from everywhere so imagine what a hypo does to your newly acquired muscle gains. Hypos are gonna set you back aren’t they so is the increased sensitivity beneficial in that case? No it’s definitely not

Depends on how you’ve got it all lined up though mate.

To address the question though most ‘thinking men’ would probably opt cycle the two rather than run them in combination.

You’d run insulin for x amount of weeks which would eventually cause insulin resistance (you’d work that out from your daily blood glucose readings if you were performing them) and then you’d drop the insulin and you’d move onto to metformin and possibly some minor carb restriction on their off time to attempt to restore some insulin sensitivity.

I wouldn’t see the attraction to using both but you might.

In my view you don’t need metformin to make you more sensitive to exogenous slin, given the doses of exogenous slin used by most people. If you need to be more sensitive to 10-20iu of humalog there’s something up. Even 5iu... It’s just unnecessary isn’t it

The metformin and amelioration of fat loss part doesn’t really apply with exogenous slin, or to a bodybuilder. Unless you’re just piling food in with no care for calories in which case you’re fucked anyway ha!

So yeah, if I was gonna do I’d cycle the two but it’s entirely dependent on your logic as with all drugs use isn’t it mate? As with anything we use.

I'm experienced with it used Lantus, Levermir and Novorapid numerous times. Either on their own or Lantus and Novorapid together.

Highest Lantus I've done is 80iu, when I use now though it's between 50-60 iu. Don't touch short acting anymore not a fan but thats just me. Ive always cycled the two (insulin and metformin) but read somewhere using metformin alongside helps to increase sensitivity when on thus making the 'slin you're using more effective for longer. Just seeing if anyone had any experience/results with this or wether it's pointless.

Never gone hypo as did my homework before using any of it and it takes a grade A moron to go hypo on slin lol. Really don't get how people go hypo on it 2bh, bodybuilding wise that is, just clearly people who havent done the research and thought fuck it I'll give it a go.

 

[Penguin]

Can be used on off days from slin.

Depends on your insulin set up etc

Don't have days off as only use Lantus now. So cycle is one shot every morning pre-breakfast

 

[Penguin]

T

Simple answer - no.

Ins - 4-6 weeks - 2 weeks on metformin then back on slin.

This is near enough to what I've always followed though mine was just 4 weeks slin then 4 weeks metformin.

 

[Sjundea]

I'm experienced with it used Lantus, Levermir and Novorapid numerous times. Either on their own or Lantus and Novorapid together.

Highest Lantus I've done is 80iu, when I use now though it's between 50-60 iu. Don't touch short acting anymore not a fan but thats just me. Ive always cycled the two (insulin and metformin) but read somewhere using metformin alongside helps to increase sensitivity when on thus making the 'slin you're using more effective for longer. Just seeing if anyone had any experience/results with this or wether it's pointless.

Never gone hypo as did my homework before using any of it and it takes a grade A moron to go hypo on slin lol. Really don't get how people go hypo on it 2bh, bodybuilding wise that is, just clearly people who havent done the research and thought fuck it I'll give it a go.

Disagree.
I am Def not a grade a moron (maybe a B), but spewing my guts mid session and finding that your missus has drunk your back up lucozade doesn't make someone moronic. You can never fully know how your body will respond. I had used it many many times prior to this.
I'd agree it's incredibly difficult to go hypo on lantus but Novo is very very possible if external factors can't be accounted for.

 

[BigChap92]

Disagree.
I am Def not a grade a moron (maybe a B), but spewing my guts mid session and finding that your missus has drunk your back up lucozade doesn't make someone moronic. You can never fully know how your body will respond. I had used it many many times prior to this.
I'd agree it's incredibly difficult to go hypo on lantus but Novo is very very possible if external factors can't be accounted for.

Yeah there’s so many factors that affect blood sugar metabolism that unless you lead an entirely robotic existence it’s hard to predict.

Have a particularly hard session and do a few extra reps and it can affect the lot. Fatigue levels, actual calorie content of food can vary, whole host of factors.

That said long acting is fairly easy to predict, no spikes, humalog is a fucking nightmare.

 

[Penguin]

Disagree.
I am Def not a grade a moron (maybe a B), but spewing my guts mid session and finding that your missus has drunk your back up lucozade doesn't make someone moronic. You can never fully know how your body will respond. I had used it many many times prior to this.
I'd agree it's incredibly difficult to go hypo on lantus but Novo is very very possible if external factors can't be accounted for.

Impossible to go hypo on Lantus unless a grade A moron. Given that trainers/bbs/weightlifters whatever tag you use eat multiple times a day then it's impossible. Moronic if you starve yourself or decide to do a keto diet while using. Even the NHS recommend diabetics who use Lantus to inject 1.5 hours before bed so yes I still stand by my statement.

Slin preworkout takes more planning as you're depleting glycogen while training too but obviously it seems you did your planning so don't know why you would disagree. Somebody else having your carbs when you're using is just extremely and of course dangerously unlucky. However I'd ask did you tell your Mrs you're using or did you do the soft route and hide it? If so then that's your problem sorry.

You can't go wrong with the 10g of carbs per 1 iu rule when starting (that's in regards to fast acting slin anyhow). Vast majority will find that they need less, mine was 6-7g carbs mark. Then you get the idiots (not saying this is you) who get the units of measurement mixed up so again yes, moronic.

Even when I've got everything covered I always have a couple packs of dextrose tabs on me. OK people may say well you could always forget but then the counter argument is if you can forget something like that, something that could prove fatal or leave lasting damage, then you shouldn't be using in the first place.

 

[Penguin]

Yeah there’s so many factors that affect blood sugar metabolism that unless you lead an entirely robotic existence it’s hard to predict.

Have a particularly hard session and do a few extra reps and it can affect the lot. Fatigue levels, actual calorie content of food can vary, whole host of factors.

That said long acting is fairly easy to predict, humalog is a fucking nightmare.

I used Novo preworkout and never had a problem with this. Had the intra-shake with me and the dextrose tabs in my pocket, I made sure to go overboard if you like so accumulated more fat than I would have liked but as we know this can easily be dieted off.

I thought it was worth the trade off 2bh. Go overboard on the carbs and then diet it off after. I think people can run into problems when they use it around training and before each meal as there's a crossover, many believe that if they take care of that initial 15 mins-1 hour later they're golden but the residue still hangs around for like 5 hours. Again though I'd personally argue just do your proper research.

Like you said too each day changes in regards to activity and blood sugar so just plan each day around that rather than having a rigid schedule.

 

[BigChap92]

I used Novo preworkout and never had a problem with this. Had the intra-shake with me and the dextrose tabs in my pocket, I made sure to go overboard if you like so accumulated more fat than I would have liked but as we know this can easily be dieted off.

I thought it was worth the trade off 2bh. Go overboard on the carbs and then diet it off after. I think people can run into problems when they use it around training and before each meal as there's a crossover, many believe that if they take care of that initial 15 mins-1 hour later they're golden but the residue still hangs around for like 5 hours. Again though I'd personally argue just do your proper research.

Like you said too each day changes in regards to activity and blood sugar so just plan each day around that rather than having a rigid schedule.

Yeah I agree mate, you need to have your precautions in place and treat it with a bit of respect as you say.

Do that and it not an issue is it.

I’ve been caught out a few times in the past but that was being a dickhead. I’d jab 10-15iu humalog, drive to the gym, drink a carb shake over the workout then drive home, cook my meals and and eat....

Was fine unless I got stuck in traffic as there was a match on at old trafford.

Naturally, repeated the error several times more just to confirm it was a foolish thing to do. Pulling up on the pavement directly outside the shop to stagger in and drink a can of coke etc

Who dares wins chap....

 

[GhostOf2Can]

Sounds like a lot of hassle to me

Does it really make that much of a difference where it’s worth the extra potential problems?

 

[BigChap92]

Sounds like a lot of hassle to me

Does it really make that much of a difference where it’s worth the extra potential problems?

Few lads swear by it but all I ever found was it blows you up to fuck and then you piss it all back off when you stop.

Don’t think I gained any muscle or weight I wouldn’t have gained without it
If I’m honest. Just got to look massive in the gym for 6 weeks at a time.

 

[GhostOf2Can]

Few lads swear by it but all I ever found was it blows you up to fuck and then you piss it all back off when you stop.

Don’t think I gained any muscle or weight I wouldn’t have gained without it
If I’m honest. Just got to look massive in the gym for 6 weeks at a time.

Seen other people use it and it looked like that’s what was happening to them tbh

Every time they dropped it they just seemed to go back to their usual size, going off pictures etc