Are You A Genetic Freak Or Freakishly Lacking In "genetics?"

Discussion in 'Fortitude Training' started by Scott Stevenson, Mar 21, 2015.

  1. Scott Stevenson

    Scott Stevenson Full Member

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  2. TheProducer

    TheProducer Top Contributor

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    Been following your work on elitefts, really enjoying the scientific approach you bring to it. The article regards to one diet fits one, snowflake made for a good read as well. Great to see that this kind of diet related study has been undertake on identical twins. Atleast it limits the amount of variables.

    Would be cool to see more videos of you/meadows/tate. I enjoyed the leg hypertrophy and me and a couple of the lads at work tried out a few movements you mentioned in there.
     
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  3. TinyTim

    TinyTim Timothy Sprague-Dawley Top Contributor

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    The greatest gains were had in those who had a molecular “signature” characterized by inactive mTOR

    That, alone, should be a great hook for this article. :)

    Baseline lean muscle mass did not explain who the responders were and neither did sex of the trainee. It was almost universal that the high-responders had this down-regulated mTOR profile(3).

    This makes it a free for all. :D

    Source: http://www.elitefts.com/education/t...dybuilding-science-to-create-a-genetic-freak/
     
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  4. TinyTim

    TinyTim Timothy Sprague-Dawley Top Contributor

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  5. Scott Stevenson

    Scott Stevenson Full Member

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    Thanks for the good words, TP. (I posted the link to the diet article you're referring to for someone last week and referred to him as "Snowflake." He laughed afterwards, but nearly got offended until he knew what I meant... LOL)

    Talked with John last night and we're gonna try to get me up to Columbus sometime soon. :)

    Thanks for those teasers, Righty. :)

    I had a fun time writing this article - I learned a ton in doing so. (Took me quite a while, but it was worth it.)

    -S
     
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  6. TinyTim

    TinyTim Timothy Sprague-Dawley Top Contributor

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    Nothing beats self-exploration IMO. :)
    Nice articles - gives me hope. Lmao.
     
  7. Hilly

    Hilly Nutritionist and Sports Therapist Moderator

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    Gives us all hope lol
     
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  8. Daz

    Daz Full Member

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    Good article but it leaves me feeling a bit conflicted.

    A lot of supplements are hell bent on increasing mTOR take forskolin for example.

    So all these supplements have it wrong?

    Isn't mTOR the body's rate of how it regenerates, so how would slowing this down actually increase gains?
     
  9. TheProducer

    TheProducer Top Contributor

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    Haha bless him! Get offended and the realises that it is infact a compliment!

    Ill look forward to seeing the video! Any ideas on what you are going to be training/going over?
     
  10. Scott Stevenson

    Scott Stevenson Full Member

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    Hey Daz,

    Some quotes from the article for ya:

    "Perhaps an inhibited mTOR profile indicates that slow n’ steady, controlled protein synthesis is a more appropriate strategy for remodeling a larger muscle cell..."

    "Once again, these results points to the possibility that “controlled” coordination of growth (as opposed to an all cyclinders firing, maxed-out protein synthetic response), as well as satellite cell involvement (see more below), are both important for packing on the beef."

    "Perhaps muscle protein synthesis represents an acute alarm reaction, whereas satellite cell activity plays a more important role over the course of larger, more pronounced, long-term increases in cell size."

    I'm not suggesting that blunting protein synthesis is advantageous, and, as noted in the article, several studies show that, overall, acute protein synthetic responses to a given condition (e.g., taking in an intra-WO supplement) are predictive of overall growth over training. So, overall, turning on protein synthesis is part of the adaptive process. However, there is so much variability and so many other important processes going on that acute protein synthesis per se, does not seem to be the most telling of whether someone will grow well or not in all circumstances.

    Just like the construction site analogy (building a mall) in the article: The rate at which 2 x 4's get used up at the construction site (protein synthesis) is not the only factor determining how fast the mall is built, when you consider that there is drywall, electrical, HVAC, painting, roof work, etc. that are all necessary for the mall (muscle cell) to be functional... Generally speaking, 2x4 inclusion in building a necessary component of building the mall, but it does not seem to be the hypertrophy-limiting aspect of fiber remodeling.

    -S
     
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  11. Scott Stevenson

    Scott Stevenson Full Member

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    LOL - It was kinda funny.

    Dunno when we'll be up there. I'm hoping sometime between May and September, when the weather is nice... LOL :)

    -S
     
  12. Daz

    Daz Full Member

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    Sorry for the late response, been hell of a stressful week.

    Kinda suspected that it would be a bit of both, like you say the body will pretty much dictate how to pack on the mass as to how it feels is best.

    Nice to know as well, given i'm no spring chicken so having to back off a bit on occasions.
     
  13. Heath

    Heath Full Member

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    This thread confuses me
     
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  14. Simon

    Simon Administrator

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    This is a picture of my training partner calves. Just imagine how good they'd be if he trained them (at all)!

    IMG_2614.jpg
     
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  15. Simon

    Simon Administrator

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    Sorry for slight thread derail, it makes me angry :D
     

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