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Pinning Test E Subq

Discussion in 'Anabolic Steroids & Prohormones' started by Simon90, Jan 1, 2021.

  1. Sjundea

    Sjundea Top Contributor

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    Less build up of scar tissue is an appeal for me. Plus on small cruise doses, I like to just jab sub q as I would hgh or peps.
    Just a way to save harpooning myself with 'larger' needles for a bit I guess.
     
    #16
  2. godsgifttoearth

    godsgifttoearth Full Member

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    A subq infection is much less catastrophic than a deep IM one. Not that it's something to regularly worry about with decent gear but its a useful "failsafe" for trying out a new lab that you have suspicions about.
     
    #17
    Sjundea likes this.
  3. spearman

    spearman Full Member

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    That was my understanding of it too.

    more frequently sub q jabs = less estrogen.
     
    #18
  4. godsgifttoearth

    godsgifttoearth Full Member

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    Injection frequency produces just as much e2, it however has a more favourable T:DHT:E2 ratio.

    As your T drops with a single injection, your e2 stays pretty flat and elevated. T is actually inhibitory of e2 expression, so the risk of e2 sides is greater when T is lower compared to e2.

    If you maintain a more stable T, you can run e2 a bit higher without needing an AI.

    If you subq, you get more e2, so it would then make sense to up the frequency to make sure T is maintained in a more favourable ratio to e2, so you get the benefits of e2 without a developing a cracking rack.
     
    #19
  5. spearman

    spearman Full Member

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    #20
  6. GhostOf2Can

    GhostOf2Can Top Contributor

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    Sounds like Phaggotry tbh
     
    #21
    SebChopChop, actin and spearman like this.
  7. godsgifttoearth

    godsgifttoearth Full Member

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    it would be very useful if the cited how they were making those claims.


    Pharmacokinetic Profile of Subcutaneous Testosterone Enanthate Delivered via a Novel, Prefilled Single‐Use Autoinjector: A Phase II Study

    pulling from that study, 50mg SC, 100mg SC, 200mg IM.

    50mg SC, 100mg SC, 200 IM

    mean t - 442.4, 895.5, 1658.7

    mean DHT/T - 0.0750, 0.0609, 0.0732

    mean e2/T - 0.0063, 0.0055, 0.0032


    50mg SC to 100mg SC is

    202% increase in total T

    81% increase in DHT to testosterone.

    87% increase in estrogen to testosterone


    100mg SC to 200mg IM is


    185% increase in T

    120% increase in DHT to T

    58% increase in estrogen to testosterone.

    that to me reads like more conversion to e2 as it hits more aramatase before getting out of the adipose tissue and less DHT as there's less to interact with 5ar. i could be making an absolute pigs ear of it tho.

    i don't understand any mechanistic action that would allow there to be less e2 for the same T load, without an increase in DHT or E2 or simply less T through elimination before it hits the bloodstream
     
    #22
  8. Reacher

    Reacher Top Contributor

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    #23
    spearman likes this.
  9. godsgifttoearth

    godsgifttoearth Full Member

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    i can't find the actual full study anywhere for this, its just the TL;DR, doesn't give much other details. the mean age of the study group is the same as the one i've posted or there abouts so it should be reasonably comparable.

    they've screened for comorbidities and then equalised for them, makes me wonder what the underlying potential issues were. you'd assume it would be stuff like BMI, however if they were all obese, by the logic i've stated you'd assume E2 would be substantially higher, its not.

    the average BMI in the study I posted is 28-29 so they were all overweight, which might be why the e2:T was much worse vs that one potentially. be interesting to see if this study had people who weren't overweight etc.
     
    #24
  10. Simon90

    Simon90 Top Contributor

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    It’s just less scar tissue that appeals to me with being younger. I’ll be like pinning an old leather boot in 10years time
     
    #25
  11. actin

    actin Balls of Stallion Full Member

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    How fcuking camp
     
    #26
  12. SebChopChop

    SebChopChop

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    I admit a lot of the science goes over me head but at the same time people can over-complicate simple things.
     
    #27