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What Not To Take With Clen


PPAR’s, such as cardarine, increase skeletal muscle fatty acid catabolism, improve insulin sensitivity, increase HDL (‘good cholesterol’), elicit anti-inflammatory activity and induce terminal differentiation (where cells become specialized) - all positive traits not typically found in a compound that cause tumor growth. However, as we all know, there are findings that PPARb/d ligands (cardarine) increase or support tumor growth by increasing the rate at which cells proliferate (by inhibiting apoptosis through phosphorylation of Akt and by increasing cyclooxygenase-2 (COX2) and vascular endothelial growth factor (VEGF) expression).

The contradictory findings could be due to differences in the model system (cancer cell line versus in vivo), differences in cell culture conditions (with and without serum) or differences in ligands. This study examined the effect of two different compounds (GW0742 and GW501516 aka cardarine) in human cancer cell lines cultured in the presence or absence of serum and compared in vitro (in a culture dish) analysis with in vivo (in a live organism) analysis.

Neither GW compound increased cell growth or phosphorylation of Akt and no increase in the expression of VEGF or COX2 were detected in any cancer cell line in the presence or absence of serum. Similarly, liver, colon and colon polyps from mice administered these compounds did not exhibit changes in these markers.

So essentially, we have a study that is at odds with other studies done, probably because of the dosing. Dose was 10mg/kg daily for 5 days, or about 160mg for a 100kg male. My personal conclusion is that this does not call into question the original studies that show the incidence of cancer, but reaffirms that length of time running this compound can not be ignored. A 5 day long cycle at a very high dose was not sufficient to cause cancer, whereas running the compound for 2 years does


Cardarine potentially only a danger with prolonged use then.

Still not enough to get me to use it like but using it for quick bursts at the end of a cut when knackered is a potential use I suppose, or the week of a competition if powerlifting.
 
Ran caradarine a year ago (cpl of tubs worth)

Can’t remember what I was expecting out of it as a while ago (I did research it obvs) but I remember thinking it was a waste of money and didn’t seem to do shit
 
Ran caradarine a year ago (cpl of tubs worth)

Can’t remember what I was expecting out of it as a while ago (I did research it obvs) but I remember thinking it was a waste of money and didn’t seem to do shit
Just coz u didnt start butting fridges dosent mesn its useless mate
 
Just coz u didnt start butting fridges dosent mesn its useless mate
Nah it’s weird mate if I take something I usually like it to make a difference with building muscle or losing fat, obvs u ain’t arsed about dat like u just like taking stuff to take it but I’m different bro
 
Nah it’s weird mate if I take something I usually like it to make a difference with building muscle or losing fat, obvs u ain’t arsed about dat like u just like taking stuff to take it but I’m different bro
Im a user not an abuser x
 
Threw me left over tren out today btw @Fatbrah srs. Only 5ml but wanna be able to enjoy the holiday

No freak outs this time (low dose) but it dawned on me today when I was talking my missus how much of a monotone joyless cabbage id been the last couple weeks. She was all happy to see me after work talking about the holiday etc and I was just thinking hopefully if I appear even more uninterested than I am now she’ll fuck off to her cousins cos I don’t want to talk to her

No good is it
 
Threw me left over tren out today btw @Fatbrah srs. Only 5ml but wanna be able to enjoy the holiday

No freak outs this time (low dose) but it dawned on me today when I was talking my missus how much of a monotone joyless cabbage id been the last couple weeks. She was all happy to see me after work talking about the holiday etc and I was just thinking hopefully if I appear even more uninterested than I am now she’ll fuck off to her cousins cos I don’t want to talk to her

No good is it
Thats it mate, wise decison la thats exactly how it makes u, unsocicable cabbage and for what? Its fuckin riduclous when ya read it out loud innit

Just literally no need, i dnt even look much shitter cnt get much shitter than shit tho can ya, every cloud
 
Threw me left over tren out today btw @Fatbrah srs. Only 5ml but wanna be able to enjoy the holiday

No freak outs this time (low dose) but it dawned on me today when I was talking my missus how much of a monotone joyless cabbage id been the last couple weeks. She was all happy to see me after work talking about the holiday etc and I was just thinking hopefully if I appear even more uninterested than I am now she’ll fuck off to her cousins cos I don’t want to talk to her

No good is it

I just think it’s like booze. Our true feelings come out when pissed/on Tren. So if I want them to fuck off when drunk or on Tren then they can fuck off and I’ll be happy about it.
 
I just think it’s like booze. Our true feelings come out when pissed/on Tren. So if I want them to fuck off when drunk or on Tren then they can fuck off and I’ll be happy about it.
Na its not ya true feelings tho if thats ya true feelings ya a very sad indivdual imo
 
I just have no interest in anything on tren. Don’t wanna socialise, don’t feel emotion, I’m bi polar as fuck and the rage is just unbearable. Even shit like driving, I’m going off at the slightest traffic infringement when normally it’d take Jamie Carragher spitting in my daughters face to get a rise out of me.

Normally I’d just laugh at them, shake my head, at most I would slide tackle them if it was warranted but that would be rare.

Just turns me into an aggy horrible cunt and it’s because of the inflammation it causes throwing everything off I reckon. Inflamed lungs and gastric tract = Less oxygen transfer and less nutrients. Add that to the snoring in your sleep and borderline apnoea, plus increased oxygen being used to metabolise your fat and you’re gonna have mush for brains
arent you.

All conjecture though, just seems a reasonable assumption based on the little I’ve managed to find out about its effect on humans.

Pile of shite anyway, look good but feel horrendous.

Good for a few weeks before a holiday or over summer when you’re off work and have no stress, at best.

Will give DHB a run at some point and see if it stands up to my stringent testing methods bruhs, that’s gotta be worth a run.
 
I just think it’s like booze. Our true feelings come out when pissed/on Tren. So if I want them to fuck off when drunk or on Tren then they can fuck off and I’ll be happy about it.
Nah I love my missus and we usually laugh all the time when together srs

I was even looking forward to seeing her, but as soon as she got home my mood just changed. Was weird and not like me when I ain’t on this crap
 
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